Fred Faulkner has identified a common scenario:
You have worked for a large firm for many years and you have made the decision to either go solo or start a small firm. You were used to having access to all your information via an Intranet, file server, and your desktop. You could practice law and let the IT department worry about when the printer jammed or if you got a virus. Now that you are solo, you are the one that has to deal with all those problems as well as practice law.
In his article Are you ready for the web-based office? he suggests alternatives that enable solos to have all the applications big firms offer.
From my point of view, the latest offerings mean I can work effectively anywhere without big firm IT department restrictions.